Hello, I am using the latest Chrome Version 41.0.2272.17 beta-m (64-bit) and AdBlock Plus 1.8.10.
My problem appeared after the last Chrome update.
When you open a new tab with YouTube or in a new window when you first go to YouTube it loads the page instantly but then it hangs for 4-5 seconds, before you can click on anything or you can search for anything.
I tried with ABP disabled on YouTube and the problem disappeared. I don't know if you can reproduce the problem but i think it is a bug in ABP with Chrome 41.