Yesterday (January 20th) when I started my Firefox 43.0.4 on Windows 7 Adblock Plus had disappeared from the Toolbar (in the Firefox add-on settings "Show in Toolbar" got disactivated and whenever I try I can't activate it, instantly gets disactivated every time I try to click on it). Since then, while Adblock still gets detected on websites with anti-ad block messages it doesn't actually block ads anymore anywhere.
I already tried uninstalling and download it again, but it's still like this.